1、The performances of gastrointestinal tract are anorexia, nausea, vomiting, diarrhea, glossitis, mouth with urine smell, oral erosion, gastrointestinal bleeding,etc.
2、The performances of nervous system are listlessness, weakness, dizziness, headache,hypomnesis, insomnia,limb numbness, burning pain in the hands and feet, patients sometimes appear lower limbs itch, allotriosmia,nerve deafness, throat and tongue muscle weakness, dysuresia, urine storage slip,etc. Patients can appear lethargy, irritability, delirious speech, muscle tremor even convulsions and coma. The causes of neurological symptoms is retention of metabolites, the electrolyte balance disorder and metabolic acidosis.
3、The performances of cardiovascular system are high blood pressure. Cardiac damage, heart failure, cardiac arrhythmia and the sclerosis of small artery and retinal arteriolar of affecting visual acuity and retinal hemorrhages, the serious patients can appear pericardial friction rub. The fewer patients have pericardial effusion even appear cardiac tamponade.
4、The serious anemia is the main symptom of hematopoietic system performance, the late patients have the bleeding tendency accompanied with subcutaneous ecchymosis, epistaxis, gingival bleeding, hematemesis, hematochezia, hematuria, intracranial bleeding, menorrhagia, few bleeding from the pericardium.
5、The performances of respiratory system are the gas smell of urine, susceptible to bronchitis, pneumonia and pleurisy. When patients appear serious metabolic acidosis, patients can have a library SiMa breath.
6、The performances of skin are dry, desquamation and malt. The black skin of few patients is duet to chronic melanin composure.