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What are the symptoms of uremia?

We often hear about the disease of uremia in our daily life, but we do not know what are the symptoms of the disease and we do not know what kind of treatment we need to completely get rid of the disease. So lets understand what are the sym...

What are the symptoms of uremia?

Jan 19, 2018 by Kidney Disease Expert

We often hear about the disease of uremia in our daily life, but we do not know what are the symptoms of the disease and we do not know what kind of treatment we need to completely get rid of the disease. So let's understand what are the symptoms of uremia in the end!

What are the symptoms of uremia?

Common symptoms: weakness, deep breathing, indifferent, delirium, convulsions, mental disorders

Respiratory symptoms

Gas exhaled in patients with urine, which is due to bacterial decomposition of urea in saliva to form ammonia; excessive body fluid may be shortness of breath, shortness of breath; acidosis, patients with slow and deep breathing, you can see the specificity of acidosis Kussmaul breathing (deep breathing). Hyperacidity, cardiac insufficiency can cause pulmonary edema or pleural effusion; increased permeability of alveolar capillary induced by uremic toxins, pulmonary congestion can cause "uremic pulmonary edema," when lung x-ray examination can occur " Butterfly wing "sign, timely diuresis or dialysis can rapidly improve the above symptoms; fibrinous pleurisy is inflammation caused by urea stimulation; lung calcification is the deposition of calcium phosphate in the lung tissue.

Gastrointestinal symptoms

The earliest symptoms of the digestive system in uremic patients are anorexia or dyspepsia, which can lead to anorexia, nausea, vomiting or diarrhea. The occurrence of these symptoms may be related to the intestinal bacteria urease will decompose urea ammonia, ammonia stimulate the gastrointestinal mucosa caused by inflammation and multiple superficial small ulcers and so on. In addition nausea, vomiting and the central nervous system dysfunction. Gastrointestinal bleeding is also more common, the incidence was significantly higher than normal, mostly due to gastric mucosal erosion or peptic ulcer.

Blood system performance

CRF patients with abnormal blood system is mainly manifested as renal anemia and bleeding tendency. Most patients are generally mild to moderate anemia, mainly due to the lack of erythropoietin, it is called renal anemia; such as accompanied by iron deficiency, malnutrition, bleeding and other factors, can increase the degree of anemia. Late CRF patients with abnormal platelet function, bleeding tendency, such as subcutaneous or mucosal bleeding, ecchymosis, gastrointestinal bleeding, cerebral hemorrhage and so on.

Neuromuscular Symptoms

Early symptoms may have insomnia , concentration of attention , hypomnesis , etc . When uremia , there may be response to indifference , Delirium , Convulsions , Hallucination , coma , mental disorder , etc . Peripheral neuropathy is also very common, sensory neuropathy is more significant, the most common is the loss of limb socks like the distribution of distribution, but also may have limb numbness, burning sensation or pain, slow reflection or disappear, and can have neuromuscular Increased excitability, such as muscle tremors, cramps, restless legs syndrome and so on. The occurrence of these symptoms and the following factors: ① accumulation of certain toxic substances may cause nerve cell degeneration; ② electrolytes and acid-base balance disorders; ③ renal hypertension caused by cerebral vasospasm, hypoxia and capillary permeability Increased, can cause brain degeneration and cerebral edema. The primary dialysis patients may have dialysis imbalance syndrome, nausea, vomiting, headache, convulsion and so on, mainly due to the imbalance of osmotic pressure in the cell and the brain edema and the increase of intracranial pressure after hemodialysis.


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