Nephrotic syndrome is a group of clinical syndromes can be caused by a variety of causes, characterized by increased glomerular basement membrane permeability, massive proteinuria, hypoproteinemia, high edema, and hyperlipidemia. So, what is the difference between children's nephrotic syndrome and adult nephrotic syndrome? Next let’s learn about it together.
Foot cell lesions in children with nephrotic syndrome are mostly manifested as cell membrane lesions, that is, foot process fusion, in fact, a simple cell membrane attack factor under the effect of increased cell membrane permeability, only by electron microscopy can be observed, so it must be checked by electron microscope. In addition, immunofluorescence assay, including IgA / M / G / C3 and all negative; light microscopic no significant change, that is basically normal. More importantly, children with primary nephrotic syndrome (minimal changes) renal interstitial changes are slight, mostly manifestations of renal tubular epithelial cell particles, vacuolar degeneration, few atrophy, fibrosis and hardening of the arteries, sparse and other interstitial lesion.
What is the difference between children's nephrotic syndrome and adult nephrotic syndrome? Through the introduction of the above content, I believe we have a certain understanding. Understand the differences between children with nephrotic syndrome and adult nephrotic syndrome, in the treatment and care should also pay more attention to active treatment. If you have any other questions, please consult our online doctor or leave us a message, we will reply to you as soon as possible.
What is the difference between children's nephrotic syndrome and adult nephrotic syndrome