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The causes of hyponatremia in nephrotic syndrome

Patients with nephrotic syndrome may occur hyponatremia, which is hyponatremia in patients with nephrotic syndrome when serum sodium and 120mmol/L are present. Next, please ask the experts to brief us about the causes of hyponatremia in nephrotic synd...

The causes of hyponatremia in nephrotic syndrome

Sep 11, 2017 by Kidney Disease Expert

Patients with nephrotic syndrome may occur hyponatremia, which is hyponatremia in patients with nephrotic syndrome when serum sodium and 120mmol/L are present. Next, please ask the experts to brief us about the causes of hyponatremia in nephrotic syndrome!

The long-term use of adrenocortical hormone in the treatment of nephrotic syndrome results in inhibition of the adrenal function, and secondary cortical dysfunction if the corticosteroid is discontinued. Long term low salt or no salt diet leads to lack of salt. Poor appetite and vomiting and diarrhea not only cause a shortage of sodium salts, but also lose much potassium and sodium salts from the gastrointestinal tract. After the use of diuretics, sodium and potassium are lost. In the case of low sodium, a large amount of electrolyte free solution can lead to hyponatremia, as well as the increase of antidiuretic hormone and the increase of water and sodium in the renal tubule, which can lead to hyponatremia.

In patients with nephrotic syndrome, hyponatremia is associated with lower levels of sodium and even lower 115mmol/L if hyponatremia is associated with hyponatremia. When blood sodium is too low, even in serum sodium 120mmol/L, the patient may also suffer from convulsions, hypotension and decreased plasma bicarbonate, resulting in transient ventilation, resulting in secondary acute respiratory alkalosis. However, if serum sodium drops slowly, although 115mmol/L, there is no obvious clinical symptoms.

Generally speaking, the prognosis of minimal change variant nephropathy and mild mesangial proliferative glomerulonephritis is good. Some patients with minimal change nephropathy can be spontaneous remission, high remission rate, but easy to relapse after remission. Early membranous nephropathy still has a high rate of treatment remission, but it is difficult to achieve remission in the late stage, but most of the disease progresses slowly and kidney failure occurs later. Mesangial capillary glomerulonephritis and severe mesangial proliferative glomerulonephritis have poor curative effect, poor prognosis and rapid access to chronic renal failure.

The causes of hyponatremia in nephrotic syndrome

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