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Common complications of nephrotic syndrome

Written by admin | Published on 2017-08-03


Nephrotic syndrome is a variety of causes of glomerular filtration membrane damage, fibrosis, and the emergence of more stubborn clinical symptoms, the most basic feature is a large number of persistent proteinuria, hypoproteinemia, high edema and Hyperlipidemia. What are the complications of nephrotic syndrome?
Infection: with the loss of a large number of proteinuria, many immunoglobulins are lost in urine and lower in plasma proteins, which affect the formation of antibodies. To reduce the immune function of patients with adrenal cortical hormone and cytotoxic drugs, also can make the patient body resistance drops, such as skin infection, primary peritoneal, respiratory tract infection, urinary tract infection, and even induce sepsis, infection and application to discover strong antibacterial drugs without renal toxicity, infection control.
Thrombosis appear: the incidence of thrombosis in patients with nephrotic syndrome, especially membranous nephropathy, can range from twenty-five percent to forty percent. The causes of thrombosis include swelling, less activity of patients, high blood lipids, loss of fibrinolytic factors and hyperlipidemia. In addition, the use of adrenal cortex hormone tends to cause hypercoagulable state of the blood.
Acute renal failure: Patients with nephrotic syndrome due to massive proteinuria, hypoalbuminemia and hyperlipidemia, body is in a low blood volume and hypercoagulable state, vomiting, diarrhea, use of antihypertensive drugs and plenty of diuresis, can decrease the renal blood perfusion decreased abruptly, which reduced glomerular filtration rate causes of acute renal failure.
Electrolyte and metabolic disorders: repeated use of diuretics or long-term unreasonable no salt, can make comprehensive secondary patients with hyponatremia and reduced blood volume nephropathy; use of adrenal cortical hormone and diuretics lead to a large number of urination, blood potassium can not get timely supplement, prone to hypokalemia.
Such a serious disease, should pay attention to it, and if there are related symptoms, should go to the hospital as soon as possible to check, if really become a patient of the disease, should also maintain a positive attitude, optimistic about.

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