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Clinical manifestations of nephrotic syndrome in children

Written by admin | Published on 2017-10-07


What are the clinical manifestations of nephrotic syndrome in children?

What are the clinical manifestations of nephrotic syndrome in children?Children with nephrotic syndrome is a common pediatric kidney disease causes from the glomerular filtration membrane increased permeability of plasma protein, albumin in urine from a large number of missing, which led to a series of pathophysiological changes. Children with nephrotic syndrome were pided into simple nephrotic syndrome, nephritis, renal disease and congenital nephrotic three types, clinical manifestations for a large number of proteinuria, hypoalbuminemia, edema, hyperlipidemia and hypercoagulability. Children with nephrotic syndrome of non infectious, easily lead to hematuria, malnutrition and other complications.

The age and gender, to preschool is the peak incidence. Simple age slants small, male more than female, male: female is about 1.5 to 3.7: 1.

Edema is the most common clinical manifestations of nephrotic syndrome. Most often as early as the parents found. Since the beginning of the eyelid, face, limbs and body. Edema gradually dentability, can appear as serous effusion hydrothorax, ascites, edema of scrotum. Boys often have significant weight can be increased from 30% to 50%. in children with severe edema in the thigh and upper arm and the inner side of the abdominal wall skin visible skin white stripes or purple lines. Edema severity and prognosis. Usually edema and often reduced urine output.

In addition to edema, children can be due to the long lost protein protein malnutrition, show pale, dry skin, dry hair yellow, nail white stripes, ear and nose cartilage weak. Children with mental tiredness and weakness, malaise, loss of appetite, sometimes diarrhea and intestinal mucosal edema, may be associated with or without infection. Long period of disease or recurrent, retardation. Nephritis children may have higher blood pressure and hematuria.

The above is on the clinical manifestations of nephrotic syndrome in children, know the clinical manifestations of nephrotic syndrome in children, it should be timely prevention, pay close attention to treatment.

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