Home > What are the complications of pediatric nephrotic syndrome?

What are the complications of pediatric nephrotic syndrome?

Written by admin | Published on 2017-06-17

  

In recent years, more and more patients with nephropathy onset, children with nephrotic syndrome is a common type of kidney disease, the incidence of the disease has brought great suffering to children with nephrotic syndrome, if got timely treatment, will lead to many concurrent symptoms, such as harm to bring the child more, then. What are the complications of nephrotic syndrome in children with? To introduce below.

The symptoms of children with nephrotic syndrome is mainly proteinuria, hypoalbuminemia and hyperlipidemia, and different degrees of edema in children with nephrotic syndrome edema of lower extremity pitting oedema, a common complication in children with nephrotic syndrome is introduced in detail as follows:

Infection: because a large number of immunoglobulins are lost in urine, plasma proteins decrease and affect antibody formation. The use of corticosteroids and cytotoxic Yao material, make the whole body resistance drops, prone to infection, such as skin infection, primary peritonitis, respiratory tract infection, urinary tract infection, and even induce sepsis.

Coronary heart disease: children with nephrotic syndrome often have hyperlipidemia and high blood coagulation state, so prone to coronary heart disease. It is reported that the incidence of myocardial infarction in nephrotic syndrome patients is 8 times higher than that in normal subjects. Coronary heart disease has become the third leading cause of death in nephrotic syndrome (second only to infection and renal failure).

Thrombosis: children with nephrotic syndrome are prone to thrombosis, especially the incidence of membranous nephropathy up to 25% to 40%. The causes of thrombus are edema, patient activity, venous stasis, high blood lipids, blood viscosity increased, the concentration of fibrinogen and high content of V, x, VII and VIII factor increases and the use of adrenal cortical hormone and prone to blood hypercoagulability,

Acute renal failure: pediatric patients with nephrotic syndrome due to massive proteinuria, hypoalbuminemia and hyperlipidemia, body is in a low blood volume and hypercoagulable state, vomiting, diarrhea, use of antihypertensive Yao and plenty of diuresis, can decrease the renal blood perfusion suddenly reduced, and the glomerular filtration rate reduce, cause acute renal failure. In addition, nephrotic syndrome is characterized by edema of the renal interstitium, concentration of proteins, formation of tubules, blockage of renal tubules, and other acute renal failure.

Electrolyte and metabolic disorders: repeated use of diuretics or long-term unreasonable no salt, can be integrated in patients with secondary hyponatremia in children with nephrotic syndrome; use of adrenal cortical hormone and diuretics lead to a large number of micturition, if not timely supplement of potassium, prone to hypokalemia.

The above is about the complication of nephrotic syndrome in children what detail, I hope parents and friends must understand the nephrotic syndrome, do early detection and early treatment, avoid the complication for children hurt.

 

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