What are the complications of nephrotic syndrome in children, many parents are worried about the problem, understand this problem contributes to the early understanding of nephrotic syndrome in children of illness complications, treatment will play a multiplier effect, so as to help people to get rid of diseases, complications of nephrotic syndrome in children as follows, we take a look at, hoping to help.
The 1. is the most common syndrome infection complications, predisposing causes: loss of IgG and complement components in urine, IgG synthesis decreased to low immune function; cellular immune dysfunction; protein malnutrition; edema; application of immunosuppressant. Respiratory tract infection is the most common, followed by skin, and primary peritonitis and other urinary tract infection. Common in children with peritonitis ascites, the pathogenic bacteria were capsular (such as Streptococcus pneumoniae and Escherichia coli) were common clinical manifestations were fever, abdominal pain and abdominal distension, abdominal muscle tension and pain is not significant.
2. electrolyte disorder hyponatremia: long term excessive salt deprivation, diuretics, infection (stress of antidiuretic hormone secretion), diarrhea, vomiting caused by manifested anorexia, fatigue, lazy words, lethargy, decreased blood pressure, shock, convulsions. Hypokalemia: diuretic hormone or diuretic, anorexia, and vomiting and diarrhea ignore the potassium induced hypocalcemia and osteoporosis. Vitamin D binding protein by urinary loss, D level decreased, intestinal calcium malabsorption, reduce the sensitivity of skeletal regulating effect on parathyroid hormone, hyperparathyroidism, in plus hormone.
3. high coagulation state and thrombosis:: increased hepatic synthesis of clotting factors; anti coagulation factor III loss in urine; hyperlipidemia blood viscosity, slow blood flow, increased platelet aggregation; infection or injury of vascular wall activate endogenous coagulation system; the use of diuretics, reduce blood volume, blood concentration; high coagulation promoting hormone application. The most common renal vein thrombosis: sudden pain or abdominal pain, non glomerular hematuria, oliguria, acute renal failure and even, ultrasonic imaging showed unilateral or bilateral renal enlargement, intravascular thrombosis can be seen. In recent years, reports of pulmonary embolism is not uncommon, there are reports of thrombosis, cerebral embolism.
The 4. Hormones Adrenal Crisis long-term use of large dose of the pituitary adrenal axis suppression, such as withdrawal too fast, suddenly interrupted, but without the occurrence of stress condition in time, children can be sudden shock, if not timely treatment to cure death.
5. acute renal failure: the possible reasons are: low blood volume caused by prerenal renal failure; glomerular lesions were severe hyperplasia significantly, GFR decreased significantly; the renal interstitial edema, protein tube obstruction caused by renal proximal tubule and renal capsule in hydrostatic pressure increased, resulting in decreased glomerular filtration efficiency.
Reminder: the above is about what about complications of nephrotic syndrome in children? What are the most common complications of nephrotic syndrome, renal vein thrombosis: sudden pain or abdominal pain, non glomerular hematuria, oliguria, acute renal failure and even, ultrasonic imaging showed unilateral or bilateral renal enlargement, intravascular thrombosis can be seen in recent years. Reports of pulmonary embolism is not uncommon, there are reports of thrombosis, cerebral embolism, hope to help you.