Nephrotic syndrome symptoms of the typical clinical manifestations, mainly high degree of edema, a large number of proteinuria, hyperlipidemia and hypoproteinemia, that is, "three high and one low." Often do not think of diet, nausea, vomiting, abdominal distension and other symptoms of gastrointestinal disorders, nephrotic syndrome symptoms can be pided into primary and secondary nephrotic syndrome two.
1, a large number of proteinuria is the most basic characteristics of nephrotic syndrome. "Bulk" proteinuria is an artificial line. At present, China is set to more than 3.5 grams / liter, most of the foreign affairs of 3.5 grams / (1.73 cubic meters 24 hours).
2, the degree of hypoproteinemia and the degree of proteinuria have a clear relationship between the level of serum albumin in patients with more than 30g / l the following.
3, hyperlipidemia, nephrotic syndrome, blood cholesterol phospholipids and triglycerides increased, hyperlipidemia and plasma albumin was negatively correlated with the main risk of hyperlipidemia can lead to cardiovascular disease. The high-risk state depends on whether hyperlipidemia is present and the level of protective lipoproteins in the blood.
4, edema, due to the loss of a large number of proteinuria, albumin decreased, colloid osmotic pressure decreased, patients often have severe edema. Edema to the face, lower limbs and scrotum of the Department of loose tissue parts of the most obvious, after the body can spread to the pleural effusion, ascites.
What symptoms signify nephrotic syndrome?
1, proteinuria: long-term proteinuria is one of the main symptoms of nephrotic syndrome.
2, hypoproteinemia: mainly plasma protein decreased, the extent of the degree of proteinuria and a significant relationship.
3, hyperlipidemia: blood triglyceride significantly increased.
4, high blood pressure: non-nephrotic syndrome, an important performance, but there is increased blood volume, water, sodium retention slide, you can also appear temporary hypertension. And type 2 primary disease nephrotic syndrome can be associated with high blood pressure.
5, gastrointestinal symptoms: due to gastrointestinal edema, often bloating, vomiting, do not think of diet, nausea and other symptoms of gastrointestinal dysfunction. In the presence of azotemia, gastrointestinal symptoms will increase.
6, the body edema: almost all the degree of different edema, edema to the scrotum, facial, lower limb most obvious. Inflammation can be sustained for several weeks or months, or swelling in the course of the entire period of swelling, in the event of infection, often make the swelling or relapse, or even azotemia.
Four typical clinical symptoms of nephrotic syndrome