Patients with nephrotic syndrome, after treatment, are less likely to have a disease if they are infected. Patients vulnerable to disease, external infection, the burden of can aggravating patient autoantibodies, some immune complex to go through the kidney filtration eduction body outside, too much burden, will add to the kidney immune complex deposition in the kidneys.
First, nephrotic syndrome complications secondary to infection: because of low albumen, extremely is local immune egg white ball is very weak, and malnutrition and significant again bump, so that the sick to make force decreases, and it is easy to disease transmission, especially the boy, in the course of the breath way or skin infection and often serious factors for kidney disease symptoms aggravate or attack again. Pneumococcal peritonitis is the more common, there are also caused by staphylococcus aureus, gram-negative bacillus peritonitis, skin infections with streptococcus cause person is given priority to, champion for cellulitis, pyoderma, or erysipelas.
Second, The complications of nephrotic syndrome are associated with electrolyte disequilibrium: a prolonged period of inequitable treatment of salt or multiple driving diuretics, which can cause hyponatremia. Low blood potassium is easily formed when the disease is diuretic in the hormone therapy procedure and does not supplement potassium as soon as possible. Widely distributed in the cells inside and outside water and electrolyte participates in the metabolism of many important functions and activities to maintain normal life activities play a very important role in the dynamic balance of water and electrolytes in the body are realized through the regulation of nerves, body fluids, clinically common water and electrolyte metabolism disorder with high permeability dehydration, low permeability dehydration, such as permeability dehydration, edema, water intoxication, hypokalemia and hyperkalemia.
Third, nephrotic syndrome complications provoked thrombosis evolution: see more with renal vein thrombosis, pulmonary artery and vein thrombosis, pulmonary embolism, peripheral venous thrombosis vasculitis. High blood fat, high blood concentration, viscosity growth, and changes of coagulant function make blood change. Human coagulation and anticoagulation systems are in a dynamic balance. Coagulation factors of small molecular weight and molecular weight of clotting factors, the coagulation factors first lost when the nephrotic syndrome, and the more serious loss, clotting factor is relative advantage at this time. In addition, serious hyperlipidemia (nephrotic syndrome of blood fat at a much higher than regular hyperlipidemia) cause blood viscous, combination cause the body in a state of high pour-point, particularly prone to blood clots. Severe nephrotic syndrome not only occurs in lower limb vein thrombosis, but also occurs in renal vein thrombosis and may cause pulmonary embolism and cerebral embolism. Thromboembolic complications are one of the most serious complications of nephrotic syndrome, such as untreated and fatal.
The fourth, the complications of nephrotic syndrome can be caused by repeated failure or acute renal failure. Because of the colloid osmotic pressure decreases, and make effective blood repeatedly capacity is not perfect, and the sick again long time limit salt water or limited use powerful diuretic or merge infection, make the blood volume more imperfect, heart discharge reducing, the sick less formation of orthostatic hypotension, shock, and even the formation of acute renal failure. This time the disease is highly concentrated in the blood, and the laboratory looks at the increase in blood and red blood cells.
Nephrotic syndrome is a recurrent risk. According to a report, over three years of follow-up to patients with nephrotic syndrome, the rate of recurrence of nephrotic syndrome was as high as 31 percent. A large part of the cause of relapse is caused by the disease itself, but also partly because of the patient's own problems.