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There are several categories of IgA nephropathy

In nephropathy, IgA nephropathy are common, but compare with nephritis, its incidence is not so high, but the disease harm to people is great, with the severity of the disease will lead to uremia, so, how to treat this disease? Lets take a...

There are several categories of IgA nephropathy

Oct 13, 2017 by Kidney Disease Expert

In nephropathy, IgA nephropathy are common, but compare with nephritis, its incidence is not so high, but the disease harm to people is great, with the severity of the disease will lead to uremia, so, how to treat this disease? Let's take a look at it.

Type I: mild lesion type. Under light microscope, most glomeruli were normal, and in some areas there were mesangial matrix hyperplasia or mesangial cell hyperplasia without tubular interstitial change. The main symptoms were paroxysmal gross hematuria.

Type II: mild lesion type. Mesangial proliferation, sclerosis, adhesion of affected glomeruli less than 50%, rare crescentic. No tubulointerstitial damage. Showed no signs of abnormal urine, patients with persistent hematuria or with mild and moderate proteinuria (less than 2.5g/24h).

Type III: focal segmental glomerulonephritis. Diffuse mesangial hyperplasia with matrix increased, with focal segmental aggravation, occasionally adherent crescent formation. The clinical manifestations were nephrotic syndrome or massive proteinuria.

Type IV: diffuse mesangial proliferative glomerulonephritis. There were diffuse mesangial hyperplasia and sclerosis in all glomeruli, with varying degrees of cell proliferation and irregular distribution. There were obvious atrophy of glomeruli, tubules and interstitial inflammation. Also known as rapidly progressive glomerulonephritis type.

Type V: diffuse sclerosing glomerulonephritis type. A stage or global sclerosis, hyaline degeneration, balloon adhesions, 50% above the crescent formation, tubulointerstitial changes heavier. The clinical manifestations were chronic renal insufficiency.

The symptoms of IgA nephropathy but should involve It differs from man to man., IgA nephropathy can live long on this issue, we have to mention uremia, because of uremia coming, often means life in jeopardy, statistics from the clinical data, once had IgA kidney, it will be 10 years from 10% to 20% people into uremia, and in 20 years the proportion will increase into uremia, clinical data showed that 20%~40% patients with IgA nephropathy in 20 years and entered uremia, less than 5% of the patients with IgA nephropathy due to acute renal failure, get effective treatment in case of failure to enter early uremia, therefore, IgA nephropathy can live long it is changed into uremia can live long problem.

The above is about the introduction of IgA nephropathy classification, if you still need to have a detailed understanding of the knowledge of kidney disease, you can consult our online experts, our experts will reply to you as soon as possible.

 

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