Acute glomerulonephritis referred to as acute nephritis, is a common immune glomerular disease in pediatrics. It is characterized by acute onset, edema, oliguria, hematuria (often accompanied by proteinuria) and hypertension. The vast majority of children with this disease for the occurrence of streptococcal infection, also known as acute streptococcal infection after nephritis. The following is the introduction of the acute glomerulonephritis pathogenesis,hope to help you .
The disease is mainly caused by the immune response caused by infection. Many suggest that certain components of streptococcal cytoplasm or secreted proteins may be the major pathogenic antigens, and that the immune response may result from the deposition of circulating immune complexes to the glomerulus. After antigen is inserted into the glomerulus, the specific antibody in the binding cycle forms an in situ immune complex and is pathogenic. The immune complex in glomeruli causes complement activation, neutrophil and monocyte infiltration, and leads to kidney disease.
What is the acute glomerulonephritis pathogenesis? Through the introduction of the above content, I believe we have a certain understanding. If suffering from acute glomerulonephritis must be timely treatment, so as not to develop chronic glomerulonephritis, and even uremia. Our hospital focus on the early symptoms of nephrotic treatment, the use of "clear poison therapy", and achieved effective results.
What is the acute glomerulonephritis pathogenesis