What are the causes of chronic nephritis in pregnancy?The reason was pregnant chronic nephritis is the attention of many people, pregnant women belong to a special group of people, once sick, the whole family will cause panic, it is necessary to introduce some pregnant reasons of chronic nephritis, the hope can cause the attention of patients and their families, and actively to make treatment.
There are many reasons for pregnancy to chronic nephritis, chronic nephritis is a group of multiple causes of chronic glomerular disease mainly glomerular lesions, but the majority of patients with unknown etiology, and there is no clear relationship between streptococcal infection, according to statistics, only 15% ~ 20% from acute glomerulonephritis and transformation, but because of subclinical acute glomerulonephritis is not easy to diagnosis. It is actually the percentage may be higher. In addition, most of the chronic nephritis patients without a history of acute nephritis, so at present there are many scholars believe that the association between chronic glomerulonephritis and acute nephritis not sure, it may be due to a variety of bacteria, viruses or protozoa by immune mechanism, inflammatory factor and non immune mechanism caused by the disease.
The etiology of chronic nephritis, the experts pointed out: is currently recognized: chronic nephritis is a cause of a group of progressive autoimmune inflammatory, primary glomerular disease. With slow onset or persistent disease, occult, longer course, with different degrees of proteinuria, hematuria and tube type the urine, with or without edema, hypertension and degree of renal dysfunction and other clinical features. Only a minority of chronic nephritis is caused by acute nephritis.
The etiology for chronic nephritis, chronic nephritis experts said: clear etiology has not been confirmed, but many speculate and infection especially viral infection. Another report sick before the contact of gasoline hydrocarbon compounds (hydrocarbons). The history of these chemicals (or can be) virus virulence factor; and there is no clear relationship streptococcal infection, according to statistics from only 15% ~ 20% acute glomerulonephritis and transformation, but due to acute glomerulonephritis subclinical diagnosis is not easy, so actually percentage may be higher.
Mesangial proliferative glomerulonephritis and its pathological characteristics under light microscope diffuse mesangial matrix increased with change as its characteristic, at the early stage of mesangial cell proliferation, late mesangial matrix increased, all lobular involvement consistent all glomeruli, glomerular capillary wall and basement membrane is normal, when the Department of membrane atypical hyperplasia, sometimes visible segmental mesangial ingrowth into endothelial basement membrane and the phenomenon, sometimes accompanied by glomerular segmental sclerosis and balloon adhesions. Electron microscope observation and mesangial matrix hyperplasia, severe cases of visible mesangial cell and matrix hyperplasia, severe cases showed segmental mesangial insertion the glomerular basement membrane, normal, electron dense material is about 1/4 ~ 1/2 case can be seen a few sparse granular and clouds in the mesangial area.
Mesangial proliferative glomerulonephritis, immune pathology is pided into the following four types: 1. Based on IgM immune globulin and C3 deposition; the IgG based immune globulin and C3 deposition; only complement C3 deposition (Note: the immunoglobulin and complement were granular deposition in the mesangial area at the same time, sometimes deposition in the glomerular capillary wall); the pathological examination was negative.
There are many reasons for pregnancy to chronic nephritis, but in order to be able to help you as soon as possible to understand the disease, you should consult the relevant expert advice, especially we also need to actively to professional hospital treatment, so as to obtain a better therapeutic effect, avoid disease caused more damage.
