How do you differentiate between the acute and chronic glomerulonephritis? Here's a look at the difference between acute glomerulonephritis and chronic glomerulonephritis.
The difference between acute chronic glomerulonephritis! Most patients with chronic nephritis are not clear, clinical features are long, and there can be a period of asymptomatic, slow progressive progression.
How to differentiate between acute and chronic glomerulonephritis?
Clinically characterized by acute onset, hematuria, proteinuria, edema, high blood pressure and glomerular filtration rate reduced to characteristics of glomerular disease, so it is often referred to as acute nephritis syndrome. Most of the clinical cases are glomerulonephritis after acute streptococcus infection.
Abbreviation for chronic nephritis, refers to the proteinuria, hematuria, hypertension, oedema as basic clinical manifestations, way is different, the onset of the disease, pathological changes slow progress, can be different degree of renal impairment, will eventually develop into a set of glomerular disease of chronic renal failure. Because of the pathologic type and disease stage of the disease, the main clinical manifestations were different, and the disease performance was perse.
What is the difference between acute and chronic glomerular nephritis?
The urine routine checks for different levels of albuminuria, scum, and red blood cells, and most patients have varying levels of hypertension and renal impairment. The clinical manifestations of chronic nephritis are similar, but their pathologic type and severity are different. According to the main pathological changes, most of the glomerular mesangial proliferative glomerulonephritis, membranous nephropathy and focal segmental glomerular sclerosis, mesangial capillaries glomerulonephritis, hyperplasia of sclerosing glomerulonephritis.
After acute streptococcus infection, the disease is delayed, and the duration of the disease can be transferred to chronic nephritis over one year. But the majority of chronic nephritis, not by acute nephritis in delay, usually due to immune mechanism, long-term effects and long-term renal hemodynamic changes caused by changes in renal blood vessels, mesangial function change.
Before it is generally believed if acute glomerulonephritis proteinuria and microscopic haematuria last over 6 months to 1 year which has been transferred to chronic, renal biopsy and clinical data in recent years, abnormal urine and renal biopsy tissue after acute nephritis activity in 2 ~ 3 years follow-up gradually disappear. Therefore, it is not possible to distinguish acute or chronic glomerulonephritis by time alone.
According to follow-up data found that acute glomerulonephritis clinical symptoms disappeared can still have residual lesions in the kidney, but sometimes with glomerular fibrosis, sometimes still found in routine urine examination protein and red blood cells, and biopsy found diffuse inflammation in the kidney lesions has been largely disappeared, only focal lesions, the so-called "defect healing." In some cases, fibrotic glomeruli were found to increase with follow-up time. In this case, the possibility of developing chronic glomerulonephritis was observed.
Chronic nephritis patients also have a tendency to acute episodes, each under the condition of the disease is relatively stable, due to respiratory tract infection or other malignant stimulation, suddenly in the short term (3 to 5 days or 1 ~ 2 days) rapid deterioration, then appear a large number of patients with proteinuria, even to the naked eye hematuria, increased tube type. Significant edema and high blood pressure, as well as deterioration of kidney function. With the proper treatment, the disease can be alleviated, basically returning to the original level, and may therefore lead to disease progression and to the stage of uremia.