Clinical manifestations of reflux nephropathy. The incidence of urinary tract infection and the severity of the symptoms were not related to the degree of reflux and the degree of renal scar. Only one case of history of infection could also have severe reflux. Children with first urinary tract infection, regardless of their age, sex and severity of symptoms should be checked. Children often under 4 years of age, recurrent urinary tract infection. Department of disease for women in youth, because of unilateral renal atrophy, renal failure, urinary tract infection, symptoms of hypertension treatment.
The most common clinical manifestation of reflux nephropathy is urinary tract infection and multiple abdominal pain. The incidence rate was 63% ~ 88% urinary tract infection; incidence rate of proteinuria was 34.5% ~ 54.7%, also can be the first symptom of reflux nephropathy, appear often in serious scar formation after a few years, prompting vesicoureteral reflux has led to glomerular lesions for poor prognosis indications. The renal function continued to deteriorate even after the operation of bladder and ureter reflux. In addition, the disease also has latent characteristics, often due to urinary tract infection during pregnancy, proteinuria, hypertension, preeclampsia or renal failure was first discovered. Inpidual patients occasionally received imaging examination for other reasons, and were found to have a single kidney or kidney scar or atrophy or because of the discovery of asymptomatic bacteriuria and taking into account the diagnosis of the disease. Some cases can be asymptomatic for a long time, until the renal insufficiency into uremia period can be diagnosed.
In the course of reflux nephritis, hypertension was found in 75% of the patients who started dialysis. Several years after successful anti reflux surgery, high blood pressure can also occur. There was no significant correlation between the severity of hypertension and the degree of reflux and urinary tract obstruction. The incidence rate of hypertension is 10.6% ~ 38.1%, which is a common complication in the late stage of reflux nephritis. About 4% of patients with severe pregnancy induced hypertension patients with reflux nephropathy; may have nocturnal urine, urine, urine concentration function abnormalities; there are 10.2% ~ 50% of reflux nephritis can lead to renal failure, the incidence of renal failure in the general age of less than 35 years of age. About half of the cases had been treated with nitrogen. Renal failure due to unilateral reflux disease is due to glomerular disease with bilateral renal involvement. This disease may also have history of enuresis (4% ~ 20%), renal calculi (2.2% ~ 18%), microscopic or gross hematuria.