Although people are living well now, many people suffer from serious kidney disease, in fact, the type of kidney disease is still a lot, such as the above mentioned lupus erythematosus nephritis this disease, then what is the four types of lupus erythematosus, such a disease requires a few clinical manifestations of a serious understanding of it.
LAccording to pathological types, lupus nephritis is classified into six types: micro - membranous type, mesangial proliferative type, focal type, diffuse type, membranous type and severe sclerosing type. In addition to severe sclerosis type of lupus nephritis late lesions, and the remaining five, four of the type of glomerular damage is serious.
Lupus nephritis type four is diffuse, light microscopy showed diffuse, procuratorial see glomerular segmental or global, active or inactive lesions. In addition to the mesangial area has been localized, stage glomerular capillaries have been involved, but not more than 50% of the total glomeruli. Glomerular injury to more than 50%. As the type and type of pathological damage is roughly the same, so the treatment program is similar, and the prognosis is more similar. Lupus nephritis type four develops to end-stage renal disease by more than 50% within 10 years, so it is important to strengthen the treatment and prolong the lifetime of this type of patient.
Treatment of lupus erythematosus type 4 should be based on clinical manifestations, laboratory tests and pathological changes to determine the treatment program. Generally believed that the clinical symptoms of mild, glomerular structure of normal or minor lesions, mild mesangial hyperplasia, antimalarial drugs can be used to treat lupus erythematosus type 4, can also be added with low-dose hormone orally. Lupus erythematosus type 4, more with hormone plus cytotoxic drug treatment, but should pay attention to this type of proteinuria after treatment is difficult to completely negative, and the disease development was benign, so in the course of treatment, to prevent excessive treatment and drug poisoning.
Expert advice: lupus nephritis four type is more serious cases, patients must be active treatment. If not timely and effective treatment, then a serious situation will lead to kidney failure, and thus endanger the lives of patients. Therefore,there is only one way in front of the patient, that is, go to a good hospital and take serious treatment.