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How to treat lupus nephritis rationally?

The treatment of lupus nephritis is a more complex clinical problem. If you are patients with lupus nephritis, please be sure to pay attention to the following points during the course of treatment: should be long-term, or even life-long tr...

How to treat lupus nephritis rationally?

Jul 23, 2017 by Kidney Disease Expert

The treatment of lupus nephritis is a more complex clinical problem. If you are patients with lupus nephritis, please be sure to pay attention to the following points during the course of treatment: should be long-term, or even life-long treatment. The disease has a strong genetic background, so far drug treatment can be a good relief of the disease, but can not be completely cured, so long-term medication. Some patients because of fear of drug side effects or listen to medical advice and unauthorized withdrawal, the condition is often repeated.

According to the degree of disease activity staging treatment. When the lupus erythematosus in the active phase, renal inflammation is very serious, usually need high doses, several drugs combined treatment, the purpose is to quickly control the inflammation, prevent kidney damage continues to increase. And when the event control is converted to low-dose drug maintenance treatment to prevent recurrence and protection of renal function. Long-term use of high-dose drug treatment will bring some complications, but if not maintenance therapy, but also cause repeated activity of lupus erythematosus, kidney damage continues to increase, and ultimately may develop for renal failure. Therefore, in the course of treatment, should be based on lupus erythematosus activity, timely adjustment of treatment. Treatment of lupus erythematosus should have a long-term planning, avoid the disease after the free withdrawal, or blind long-term medication.

The treatment program varies from person to person. Lupus nephritis severity varies, there are many types, for different pathological types should take a different treatment program. Currently widely used in large doses of hormones combined with cyclophosphamide intravenous treatment is not suitable for all patients with lupus nephritis. Should be based on specific conditions and pathological type of renal biopsy, under the guidance of a doctor in the selective treatment of drugs. In the long-term maintenance treatment, the combination of Chinese and Western therapy is not only effective, and fewer side effects, the patient can live and work.

Attention to prevention and treatment of complications. This is often overlooked. Lupus nephritis patients in the treatment process is prone to a variety of complications, such as infection, cardiovascular complications, femoral head necrosis, severe cases can be life-threatening. The key to reducing complications is the rational use of anti-lupus drugs, regular follow-up early detection and treatment. In the use of high-dose drug treatment, should be relatively isolated, not to public places, pay attention to climate change, fever and other symptoms of infection should be timely treatment.

Prevention of lupus erythematosus recurrence. Any infection, sun exposure, exposure to chemicals or pregnancy can induce lupus erythematosus activity. Female patients should avoid pregnancy before the condition is completely controlled. Such as must be pregnant, but also must be under the guidance of a doctor.

Emphasizing the concept of holistic treatment. As lupus erythematosus is a systemic disease, so in the control of lupus nephritis activity, protection of renal function at the same time, should pay attention to other important organs such as heart, lung or brain treatment and functional protection.

In summary, patients with lupus nephritis should choose a regular hospital, according to their doctor's condition characteristics, to develop a long-term treatment plan, and regular review. So as to effectively control the disease, the greatest degree of reduction of drug complications, to maintain a better quality of life and ability to work.

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