The modern people's life quality is improved, due to irregular life habits, coupled with the long-term diet is not healthy, causing more and more people get sick, sick naturally we want to take medicine, although drugs can help us to cure the disease, but the drugs can also have side effects, some of the human body as the saying goes: "is the three drug virus." so I was friends for five kinds of drugs in the life most of renal injury, a look at it!
1, antipyretic and analgesic
Antipyretic analgesic drugs is an important injury to the kidney. Cold medicine, such as analgin, Kangle Biyan tablets, Compound Pseudoephedrine Hydrochloride Sustained Release Capsules; acetaminophen, painkillers, such as Bloven, indomethacin, naproxen, diclofenac sodium preparation, compound Paracetamol Tablets, celecoxib, can cause kidney damage.
2 antihypertensive drugs
The commonly used diuretic antihypertensive drugs, angiotensin converting enzyme inhibitors and angiotensin receptor antagonists may cause kidney damage. Three drugs may cause acute interstitial nephritis, which may also reduce renal perfusion caused by acute renal failure. After two of the renal function, severe damage patients, sometimes causing the deterioration of renal function in the short term, in this case, bilateral renal artery stenosis, while the use of diuretics, non steroidal anti-inflammatory drugs, heart failure, patients are more prone to dehydration.
3, contrast agent
The contrast agent can not only cause renal vasoconstriction induced renal damage, can also stimulate oxygen generation, direct injury of renal tubular epithelial cells. The use of contrast agents, should fully assess the risk for patients with chronic renal insufficiency, diabetes, hypertension and other risk factors in elderly patients, such as recommended permeability, low viscosity, non ionic contrast agent, and to reduce the dosage, to avoid repeated use in the short term.
4, Chinese herbal medicine
Chinese herbal medicine is a very important class of drug induced acute kidney injury in our country. Including renal injury be common herbs: Chinese herbs have mufangji, tetrandrine, Aristolochia, Magnolia officinalis, Herba Aristolochiae, Kuding tea; the animal medicine cantharidin, fish bile, hippocampus, centipede and the traditional Chinese medicine venom; mineral containing arsenic (arsenic and arsenic stone, etc), mercury (class of cinnabar and HgCl2 etc.), plumbiferous (Qian Dan) and alum; the compound Chinese medicine including Guanxinsuhe pills, Ganluxiaodu Dan, fukefenqing pills, angelica four inverse soup.
5, antibacterial drugs
Aminoglycoside antibiotics (neomycin or gentamicin) antimicrobial drugs such nephrotoxic drugs, is the most common cause of drug-induced renal injury. The clinical manifestations of renal injury were hematuria, proteinuria and urinary tube, severe oliguria, anuria or acute renal failure. Penicillin or cephalosporin these two kinds of drugs can cause allergic interstitial nephritis, rash, arthralgia, fever and other systemic symptoms. Other quinolones (ciprofloxacin and norfloxacin), erythromycin, lincomycin, vancomycin, norvancomycin and antiviral drugs (such as A Silowe, lamivudine and interferon) can also cause kidney injury.
The above five drugs introduced in the life most of renal injury, hope to know the friends, usually ill medication must pay more attention to, so as not to endanger their health.