Kidney problems during pregnancy is due to pregnancy induced renal lesions, such as pyelonephritis, acute renal failure in pregnancy, postpartum idiopathic acute renal failure and pregnancy induced hypertension syndrome caused by renal changes.
Kidney problems during pregnancy is a variety of physiological changes in pregnant women in all aspects of renal function and hemodynamics, which may cause kidney by pathological damage, and renal dysfunction, especially the kidney disease of women, if not active prevention, may cause primary disease recurrence and aggravation, and endanger the fetus.
Pregnancy kidney disease is due to pregnancy induced renal lesions, such as pyelonephritis, acute renal failure in pregnancy, postpartum idiopathic acute renal failure and pregnancy induced hypertension syndrome caused by renal changes.
The clinical manifestations of moderate hypertension, proteinuria and edema. About 1/3 cases manifested as nephrotic syndrome, are non selective proteinuria. There may be severe preeclampsia, eclampsia and acute renal failure.
Physiological changes during pregnancy can also lead to renal function. From the mid pregnancy rate can begin pregnant renal blood flow and glomerular filtration increased 30%-50%, continued to gradually recover. After the birth of normal pregnant women serum creatinine was 44-53 mol/L (0.5-0.6mg/dl), such as serum creatinine than 71-88 mol/L (0.8-1mg/dl), often suggesting the decline of renal function during pregnancy. Easy to have water sodium retention, about 20% pregnant women may have a small amount of protein in the urine. The basic pathophysiology of pregnancy induced hypertension syndrome is the change of various organs of systemic small artery spasm induced hypertension and systemic injury. Manifestations of renal blood flow and glomerular filtration rate decreased with hypoxia in glomerular capillary permeability increased. Renal parenchyma is serious ischemia can produce glomerular and tubular damage and renal cortical necrosis.
Kidney problems during pregnancy are four common:
(1) the causes of pyelonephritis: uterus oppression ureter ureter, hypotonia, expansion and urinary retention, the formation of hydronephrosis.
(2): pregnancy induced hypertension syndrome occurs after 24 weeks of pregnancy, the majority can quickly cure after termination of pregnancy.
(3) acute renal failure occurred in early pregnancy: pregnancy 3 months and at the end of 3 months. In the early stage of 10-12 week peak occurs mainly in septic abortion, a secondary to water and salt of hyperemesis gravidarum lost. In the late 34-40 week peak, mainly by preeclampsia, eclampsia of pregnancy induced hypertension syndrome due. Followed by obstetric complications such as placental abruption, amniotic fluid embolism and hemorrhage. A few acute fatty liver of pregnancy.
(4) postpartum idiopathic acute renal failure: postpartum day to postpartum 6 weeks of pregnancy and childbirth. Normal. Most of the cases with microangiopathic hemolytic anemia, can be associated with fever, heart failure and epileptic seizures. The etiology may be related to viral infection, ergot preparation and oxytocin use and placental debris retention relevant.