Diabetic nephropathy is one of the complications of diabetes, if not timely treatment will endanger the lives of patients. Diabetic nephropathy treatment is more complex, then, what can treat diabetic nephropathy?
what can treat diabetic nephropathy?
Strict control of blood sugar
This is the most fundamental measures in the emergence of clinical diabetic nephropathy, that is, early in diabetes, with insulin pump or multiple subcutaneous injection of insulin strict control of diabetes, so that blood sugar remained normal, can delay or even prevent the occurrence and development of diabetic nephropathy, Reduce increased glomerular filtration rate and improve microalbuminuria. Is also beneficial for other complications.
Control of hypertension
Hypertension can promote the development of renal failure, effective antihypertensive therapy can slow down the rate of decline in glomerular filtration rate, reduce urinary albumin discharge. Angiotensin-converting enzyme inhibitors or angiotensin II receptor antagonists can be used as the preferred drug, often need to combine other antihypertensive drugs. Other antihypertensive drugs such as calcium antagonists, diuretics, beta blockers, methyldopa, and clonidine are also effective. Diabetic patients with blood pressure ≥ 130 / 80mmhg should use antihypertensive drugs, should be controlled at 130 // 80mmhg the following. With antihypertensive drugs, the relatively healthy glomeruli due to decreased glomerular capillary pressure and continue to survive, and the destruction of the glomerular quickly blocked, the water can not be filtered, the protein can not leak. It was observed that blood pressure from 160:30 95mmhg down to 135 / / 85-mmhg, urinary protein excretion was significantly reduced, glomerular filtration rate decreased from lml // min to 0.35ml / min month The Diabetic nephropathy in patients with survival was significantly longer, 10 years before the antihypertensive treatment mortality rate of 50 %% - 70 %%, after treatment to 18 %%. Antihypertensive therapy is also beneficial for diabetic retinopathy.
Limit protein intake
Properly reduce the amount of protein in the diet (0.8 / kg • d) can reduce the pressure in the glomerulus, reduce the high filtration and reduce proteinuria. On the contrary, to high protein diet will increase the glomerular histopathological changes. Renal dysfunction has been more should limit the intake of protein, and should eat with the necessary high amino acid protein.
Dialysis and kidney transplantation
In the event of renal failure, dialysis and kidney transplantation are the only effective way. Kidney transplantation is the best way to treat diabetic uremia, better than dialysis. Patients with age> 65 years were poorly transplanted.
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