What causes high creatinine levels? Serum creatinine can be more accurate response to renal parenchymal damage, not sensitive indicators. Because the glomerular filtration rate decreased to normal 1/3, the serum creatinine was significantly increased. Meaning that because the human kidney metabolic ability, when the kidney injury is generally mild when the general discomfort is not obvious, so when many people really appear nausea, vomiting, dizziness, in fact, the kidneys have been seriously injured, then the serum creatinine began to rise significantly. The Blood creatinine more than 707umol / L is uremia, blood creatinine accumulation in the human body caused great harm to the human body, often nausea, vomiting and night can not lie down the symptoms.
What number of creatinine on behalf of what kind of condition?
(1) compensatory period, serum creatinine 141.4 ~ 177.O microgram molecules / L (1.6 ~ 2.0mg / dl), nephrons by 20% to 25%, by compensatory renal excretion and regulation function is still good, if there is proteinuria , The patient may have mild eyelid edema in the morning, but generally no obvious symptoms.
(2) decompensated (ie, azotemia), serum creatinine 185.9 ~ 442.6mmol / L (2.1 ~ 5.0mg / dl), renal units decreased by 50% to 70%, renal excretion and regulatory dysfunction, Nocturia, fatigue, edema, loss of appetite, nausea and mild anemia, occasional acidosis.
(3) decompensated late (ie, pre-uremia), serum creatinine> 442.6 ~ 708.2 micrograms of molecules / L (5.0 ~ 8.0mg / dl), nephrons by 70% to 90%, patients often severe anemia, edema, May have nausea, vomiting, metabolic acidosis, hypocalcemia and hyperphosphatemia.
(4) uremia, serum creatinine> 708.2 micrograms of molecules / liter (8.0mg / dl), systemic symptoms of severe poisoning, there are a lot of water in the body retention.
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