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Gout uric acid reducing "kidney" is important

admin TAGS: 2017-10-12 16:38

With the development of society and the improvement of living standards, gout has gradually become a common disease of the common people. At present, the prevalence of hyperuricemia in China is as high as 10% -20% and the prevalence of gout is 1.04% -2.0%. In the 20 years from 1980 to 1999, the prevalence of hyperuricemia is nearly 20 times higher.

Hyperuricemia is the fourth highest level after hypertension, hyperglycemia and hyperlipidemia, but we are far less aware of its traditional "three high", leading to gout treatment is not standardized, poor treatment of patients with poor compliance.

The risk of hyperuricemia to the kidneys

For the treatment of the disease, we should fully weigh the pros and cons of medication, can not one-sided emphasis on the side effects of drugs, while ignoring the disease itself on the body damage. In fact, hyperuricemia itself is a great threat to the kidneys, uric acid deposition in human organs and tissues of the harm is far greater than joint pain, the most important of which is kidney damage. 70% of the body's uric acid need to be excreted through the kidneys, when the uric acid level is too high, more than the solubility in the blood, it will be deposited in the kidney, on the one hand directly damage the kidneys, on the other hand induced mononuclear cells and neutrophils , The release of inflammatory factors, increased kidney damage.

Uric acid nephropathy common performance

Acute uric acid nephropathy: rapid onset, a large number of uric acid crystals deposited in the renal interstitial and renal tubular, tubular tubules filled with uric acid, resulting in oliguria, anuria, acute renal failure; chronic uric acid nephropathy: Urinate crystallization in the renal interstitial deposition, onset of occult, early manifested only mild low back pain and intermittent proteinuria and microscopic hematuria, with the progress of the disease can be developed for persistent proteinuria, gross hematuria, high blood pressure; Uric acid kidney stones: urate crystals deposited in the kidney to form stones, can cause renal colic, hematuria, urinary tract infections and urinary tract obstruction and other symptoms.

Reduced uric acid treatment can delay or improve the damage of hyperuricemia to the kidneys.

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