Tong shanTang kidney disease blog

www.kidneytcm@yahoo.com

Tongshantang Blog :

Tongshantang hospital blog provides kidney failure,ckd and all kinds of kidney problem as well as diet and nursing knowledge You can reach me at kidneytcm@yahoo.com

Nephropathy associated with hyperuricemia: how to treat?

admin TAGS: 2017-10-11 14:56

Hyperuricemia (HUA), urate deposition in the kidney can lead to chronic urate nephropathy, acute uric acid nephropathy and uric acid nephrolithiasis; on the other hand, kidney disease can influence the excretion of uric acid, the occurrence of secondary HUA. HUA has been shown to be an independent risk factor for chronic kidney disease. Recently, our country issued the first HUA multidisciplinary expert consensus - "multidisciplinary expert consensus on the diagnosis and treatment of  related diseases of hyperuricemia in China".

The timing of treatment and target target value were similar to that of chronic urate. Nephrosis. HUA treatment options for chronic kidney disease are based on primary disease, complications, and renal function. NSAIDs should not be used in patients with chronic kidney disease (G4 to 5) with acute exacerbation of gout. Oral corticosteroids may be given orally or injected with intra-articular injection, and low-dose colchicine can be used according to eGFR.

Lowering uric acid in patients with chronic kidney disease can reduce glomerular uric acid burden and delay progression of chronic kidney disease, and according to the principle of inpidualized treatment, the drugs for inhibiting uric acid production and / or urate removing drugs are selected. Impaired renal function may increase allopurinol toxicity, treatment needs from low starting dose and careful titration. The use of Non GM in patients with mild to moderate renal dysfunction (G1 to 3) and patients with mild to moderate liver injury (Child-Pugh grade A/B) were not required to adjust doses, and G4 to 5 patients were treated with caution. Febuxostat hypersensitivity syndrome and lower incidence of allopurinol; uricosuric drugs benzene bromine Malone can be mild to moderate renal insufficiency (for eGFR 20 to 60 ml/min/1.73 patients, 50 mg/d m2) recommended, uric acid nephrolithiasis and severe renal insufficiency (eGFR<20 ml/min/1.73 m2) disabled patients. To prevent the onset of gout in patients with chronic kidney disease treated with uric acid lowering treatment, prophylactic colchicine should be used at the same time. EGFR<10, ml/min/1.73, M2, or dialysis patients are disabled and may be considered for short-term use of small doses of glucocorticoids.

Nephropathy associated with hyperuricemia: how to treat?
Nephropathy associated with hyperuricemia: how to treat?

 

 

Latest related articles:


  • What causes protein in urine in children?

    What causes protein in urine in children?

    We all know that when we have proteinuria, it often means that we have kidney problems, similarly, urinary protein in children is no exception, when children with urinary protein, parents must pay attention to, in time with the hospital for...

  • How to check whether kidney is healthy from feet?

    How to check whether kidney is healthy from feet?

    Foot is the most concentrated parts of the acupuncture points, but also the second heart of the human body. But do you know that? We can also check whether kidney is healthy from feet. Lets take a look at the following! 1.Toe Our little toe...

  • How to prevent recurrence of kidney disease?

    How to prevent recurrence of kidney disease?

    Life is in the trough, people often have self-denial, many patients think they cant do anything after they get sick, the impact of this self-abandonment of the mentality is often much more greater than the kidney disease itself. With the pa...

  • Effective methods of eliminating edema in patients with neph

    Effective methods of eliminating edema in patients with neph

    Many people initially found themselves suffering from kidney disease that began with edema. Because edema is one of the earliest symptoms of kidney disease. So how to eliminate edema in patients with kidney disease ? First of all to know: w...

  • What kind of cold medicine is good for kidneys?

    What kind of cold medicine is good for kidneys?

    Just entered into October, most areas temperature began to decreased, cold people gradually increased. Most of the kidney friends in the autumn and winter and spring frequent cold, upper respiratory tract infection and so on. Many patients...

  • Walk on tiptoe can protect the kidney

    Walk on tiptoe can protect the kidney

    With the increase of age, the elderly kidney gradually decline, Chinese medicine believes that the kidney is the congenital root, and closely related to bones, teeth and ears, therefore, the main decline of kidney qi in the elderly is weakn...

  • What situations prone to kidney disease?

    What situations prone to kidney disease?

    Kidney disease is pided into acute and chronic. Among them, chronic kidney disease is more common. Early kidney disease, mostly no symptoms. If you do not pay attention to abnormal urine, urine changes, or no obvious edema, low back pain, o...

  • What are the four major causes of urinary protein?

    What are the four major causes of urinary protein?

    Talking about urinary protein, many patients are not calm, it seems that since there is urine protein, their own mood is like a roller coaster, with the protein quantitative changes, mood is unstable. Anxious panic is easy to go wrong, and...