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What is the difference between glomerulonephritis and interstitial nephritis?

admin TAGS: 2017-09-27 11:11

What is the difference between glomerulonephritis and interstitial nephritis? Glomerulonephritis generally referred to as nephritis, lesions mainly occur in the glomerular, clinical manifestations of hematuria, proteinuria, edema, hypertension, some patients with renal insufficiency. According to renal biopsy examination obtained renal pathological manifestations are pided into IgA nephropathy, mesangial proliferative glomerulonephritis, minimal lesions, membranous nephropathy, focal stage glomerulosclerosis, membranoproliferative glomerulonephritis and other primary glomerulonephritis, including lupus nephritis, vascular inflammatory renal damage and secondary glomerulonephritis caused by some rheumatic diseases. The treatment is different depending on the clinical manifestations of renal pathology. Therefore, patients with glomerulonephritis often need to do renal biopsy.

difference between glomerulonephritis and interstitial nephritis
What is the difference between glomerulonephritis and interstitial nephritis?

Interstitial nephritis is often induced by infection, urinary tract obstruction and reflux, autoimmune diseases, drugs, metabolic poisons, radioactive damage, hereditary diseases. Clinical manifestations of water, electrolyte and acid-base balance disorders and anemia, renal insufficiency, there may be diabetes, amino acid urine, phosphate urine, renal tubular proteinuria and so on. Treatment is mainly to eliminate the predisposing factors, the treatment of primary disease and symptomatic treatment. Pyelonephritis (infectious interstitial nephritis) is mainly bacterial (a very small number of viruses, fungi, chlamydia, mycoplasma) inflammation of the renal pelvic mucosa caused by infection. Clinical manifestations of lumbar discomfort, intermittent urinary frequency, urination discomfort, may be associated with fatigue, fever, loss of appetite and renal tubular injury, continuous development of the disease can lead to uremia. Acute infection, systemic infection symptoms are obvious, often include fever, chills, low back pain and so on. Long-term use of nephrotoxic drugs (analgesics, heavy metal preparations, aristolochic medicine, etc.) is also an important reason.

The above is a brief introduction to the difference between glomerulonephritis and interstitial nephritis, for reference only. No matter what kinds of nephritis, as long as there are perfect and effective treatment programs, patients can receive good therapeutic effect.

 

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