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How long does it take to cure an acute nephritis?

admin TAGS: 2017-09-17 16:45

How long does it take to cure an acute nephritis? Acute nephritis disease development is fast, the treatment program should be fully improved. In recent years, the development of treatment is relatively large, the treatment effect is also significantly improved. The following will introduce how long does it take to cure an acute nephritis?

Acute period treatment: the key of this stage is to have early diagnosis, take timely immunosuppressive treatment directed at the immune response and inflammatory processes. Specific treatment methods are as follows: A. corticosteroids and immunosuppressive drugs: steroid hormones and cytotoxic drugs on the basis of conventional treatment plus high-dose methylprednisolone shock treatment (1 g / day × 3 days for a course of treatment, after intermittent 3 to 4 days repeated 1 to 2 courses). This treatment regimen is used when serum creatinine is less than 707 micromoles / liter (80 mg / l). B. Plasma Displacement Therapy: This therapy has a good effect on acute progressive nephritis type I, especially in the early stages of disease, serum creatinine less than 530 micromoles / liter (6 mg / dL) before the majority of patients will be improved, and the circulating antibody disappeared within 1 to 2 weeks. After the disappearance of the antibody continue to take prednisone treatment gradually decreased after a few months. The therapy also has a reliable effect on type Ⅱ. C. quadruple therapy: corticosteroids, cytotoxic drugs, anticoagulation and antiplatelet aggregation drugs in combination;

recurrence and exacerbation of treatment: in this disease in type Ⅰ and Ⅱ type have possibility of recurrence after clinically relieved, often in a few months to several years recurrence. And then the treatment can be relieved again. Treatment process is often associated with infection, should actively control the infection;

Chronic treatment: The disease control after active lesions did not prevent its development to chronicity. For chronic patients, long-term use of immunosuppressive drugs side effects are serious, generally limiting the above immunosuppressive therapy. For patients with chronic phase who enter uremia should start dialysis as soon as possible. The disease is easy to relapse after renal transplantation, especially in the blood antibody titer is high, it should be stable in the disease after six months of renal transplantation.

Generally considered that the prognosis of acute nephritis is good, it is a self-limiting disease, most patients without special treatment, after 6 to 8 weeks after the self-improvement in children 85% to 90% in adults 60% to 75% can be fully restored. But some patients with severe complications and persistent healing, although the strengthening of treatment, can also be converted to chronic glomerulonephritis, and even the development of end-stage renal disease. The disease course of adults is longer than children. Children have better prognosis of acute nephritis, less combined with severe complications, but the disease easily relapse caused by repeated infection. The prognosis of adult acute nephritis is inconsistent, and some believe that the prognosis is poor, there are reports of adult patients recovered slowly, but the overall prognosis is good.

 

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